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Profluent, an Emeryville-based AI biotech startup founded in 2022 by Ali Madani, raised $106 million on November 19, 2025, led by Altimeter Capital and Bezos Expeditions, bringing its total funding to $150 million and valuing it at nearly $1 billion. The company has achieved breakthroughs like the AI-designed OpenCRISPR-1 system for precise genome editing and ProGen models generating functional proteins. The new funds will scale computational resources for massive protein datasets and advance applications in therapeutics, agriculture, and materials.

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Jeff Bezos's investment fuels Profluent's quest to design proteins and genome editors using AI, pushing biotech boundaries.

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The House Oversight Committee, led by Chairman James Comer, agreed with former President Bill Clinton and Hillary Clinton on depositions set for late February, avoiding a contempt vote after they resisted subpoenas. The probe examines Jeffrey Epstein's sex-trafficking network, government file handling, and new details like photos of Bill Clinton with Ghislaine Maxwell and emails showing her role in Clinton Global Initiative funding. Republicans highlight flight logs and photos to press questions, while Clinton demands public hearings and full document releases; Maxwell invoked the Fifth over 100 times in her deposition and denied wrongdoing by the Clintons.

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Bill Clinton called it a 'kangaroo court,' but Republicans are pushing ahead with closed-door depositions to dig into his Epstein ties.

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The 50-year-old businessman, known for mentoring young Nigerians and his lavish 2021 mother's burial, posted clips from a high-end Palm Jumeirah resort, highlighting a luxury escape far from everyday struggles. His recent endorsement of President Tinubu's 2027 re-election, as economic pressures like 15.1% inflation and projected poverty for 141 million people persist, amplified the criticism labeling the posts as tone-deaf. While supporters like Cubana Chief Priest defend his hard-earned enjoyment of 20 years with wife Lush Eby, detractors see it fueling class divides and political resentment.

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Obi Cubana shared upbeat videos of infinity pools and turquoise jumps in Dubai, celebrating Valentine's with his wife—footage that hit a nerve back home amid Nigeria's hardships.

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On Sunday, Fugal posted a graphic demanding accountability for what he called the largest child abuse ring in history, captioning it 'We the people need justice & accountability.' The post came as the DOJ released nearly 3.5 million pages on January 30, 2026, under the Epstein Files Transparency Act, including videos, images, flight logs, and records from Epstein and Ghislaine Maxwell cases. Attorney General Pam Bondi listed hundreds of politically exposed persons on February 15, while lawmakers from both parties questioned the process and experts noted mentions do not imply guilt. Fugal's message echoed widespread calls online for a full reckoning, though no new prosecutions have emerged.

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Brandon Fugal, owner of the mysterious Skinwalker Ranch, shared a striking message amid the DOJ's massive Epstein document drop: if exposing the biggest child abuse ring would collapse the world, then let it collapse.

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In a January 17 speech, Bukele dismissed investing in education for gang members who've 'graduated from the university of crime,' pointing to El Salvador's homicide rate plummeting from 106 per 100,000 in 2015 to a record low 1.3 in 2025 after mass arrests of over 80,000 suspects and a massive prison. Supporters like Elon Musk and U.S. Senator Mike Lee praise the results as a model for safer streets, while critics from Amnesty International and Human Rights Watch highlight arbitrary detentions, torture reports, and over 260 detainee deaths since 2022. Bukele's approach, followed by a quip about a pickpocket caught '3 Doritos later,' underscores his push for swift enforcement amid global divides on crime and rights.

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Surrounded by security forces and seated prisoners, El Salvador's President Nayib Bukele declared criminals beyond redemption by education—only force works.

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John Smith led Labour from July 1992 until his sudden heart attack death on May 12, 1994, at age 55, boosting the party to double-digit poll leads with his dry wit, Christian faith, and traditional values. He sidelined modernizers like Mandelson, earning praise as the 'best prime minister we never had' and 'last honest leader' from voices across the spectrum. The nostalgia surges now as Prime Minister Keir Starmer, who briefly appointed then sacked Mandelson as US ambassador, faces resignation calls after his chief of staff quit over the hire. While most mourn a lost era of integrity, a few question if Smith's government would have endured longer than past short-lived Labour terms.

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As fresh Epstein revelations force Peter Mandelson's resignation, a post recalls John Smith—the Labour leader who kept him at arm's length during his principled 22-month tenure.

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Reports today detail problems like password changes, failed recoveries, and account restrictions across PayPal, Google, LinkedIn, and Payoneer. Unauthorized transactions held up funds in some PayPal cases, while LinkedIn users dealt with repeated lockouts. No outages or breaches show on status pages, with experts pointing to phishing, weak passwords, or old leaks like the 15 million PayPal credentials exposed earlier this year. Platforms urge quick recovery tries, two-factor setup, and official support contacts for fixes.

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One person lost access to a Gmail account from 2007, despite every recovery step they knew. Others faced unauthorized logins and locked PayPal funds, turning frustration into urgent pleas for help.

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Protests against Iran's regime entered their second month after exploding on January 8, following Reza Pahlavi's call for unified action amid economic hardship and resentment. Security forces face accusations of massacring thousands, with human rights groups like Amnesty International documenting over 6,000 deaths since late December and up to 36,000 in early January alone. Pahlavi, son of the last shah, seeks a transitional role for free elections, drawing fervent support but also debate over monarchy versus republic, as seen in diaspora rallies and polls. Meanwhile, President Trump noted progress in indirect nuclear talks with Iran on February 7.

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Chants of 'Long live the King' echo through Iran's streets as protesters wave the old Lion and Sun flag, defying gunfire in a fight for change.

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Vibe coding lets anyone build software quickly using casual AI prompts, popularized by Andrej Karpathy for rapid prototypes with tools like Cursor and Claude. Enthusiasts, including YC's Garry Tan, praise it for speeding up startups with voice inputs and auto DevOps. But critics highlight maintenance costs, reliability issues for enterprises, debugging nightmares, and the need for marketing—arguing polished SaaS tools like Rippling still dominate for scale and compliance.

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Yuchen Jin sarcastically asked why solo founders aren't vibe-coding full enterprise suites like Slack and Jira over a weekend. His post drew hundreds of likes and replies unpacking the trend's real limits.

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A graphic from TouchlineX sparked thousands of replies by asking fans to axe one from this stacked lineup of Spain's midfield greats, who powered World Cup and Euros triumphs. Rodri's backers highlight his 2024 Ballon d'Or win, 74-game unbeaten streak at Manchester City, and Euro 2024 role, calling him indispensable in today's game. Others defend the golden generation's magic from Xavi, Iniesta, and Alonso, while some point to Fàbregas or Alonso as the pick, fueling a clash between team dynasty and individual brilliance.

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Imagine Spain's legendary midfield packed with prime Xavi, Iniesta, Busquets, Alonso, Fàbregas, Silva, and Rodri. Fans face the tough call: who gets dropped?

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