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Profluent, an Emeryville-based AI biotech startup founded in 2022 by Ali Madani, raised $106 million on November 19, 2025, led by Altimeter Capital and Bezos Expeditions, bringing its total funding to $150 million and valuing it at nearly $1 billion. The company has achieved breakthroughs like the AI-designed OpenCRISPR-1 system for precise genome editing and ProGen models generating functional proteins. The new funds will scale computational resources for massive protein datasets and advance applications in therapeutics, agriculture, and materials.

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Jeff Bezos's investment fuels Profluent's quest to design proteins and genome editors using AI, pushing biotech boundaries.

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FC Barcelona wished Muslims 'Eid Mubarak' during Ramadan but did not post Easter greetings for Christians. Real Madrid similarly failed to share Easter messages despite having a cross on its crest.

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Olivia Miles surpassed the record previously held by Caitlin Clark and Paige Bueckers, who achieved the milestone in 19 games. The achievement highlights her strong rookie performance in the WNBA.

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Coldplay Access shared a dramatic announcement Tuesday claiming the band was splitting after Moon Music and their tour, with Chris Martin eyeing Hollywood and Jonny Buckland tending sheep. Heartbroken reactions flooded in, like one user's 'BITCH MY HEART SKIPPED A BEAT,' though savvy fans spotted the April Fool's joke right away. No official word from Coldplay, whose Music of the Spheres tour runs through 2026 and latest album earned strong reviews.

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A Brazilian fan account's post screamed 'THE END OF COLDPLAY!' with a 1998-2026 stamp, leaving fans pleading 'What do you mean end of Coldplay???' before realizing it was April 1.

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The San Diego Padres rallied for a 5-4 comeback win over the Cincinnati Reds, capped by Tatis' solo homer off rookie Chase Petty—his second of the season and second career walk-off. Tatis had battled a power drought with just one homer in 246 at-bats before heating up lately, going 2-for-5 with two RBI in the game. Samad Taylor's eighth-inning single tied it at 4, improving San Diego to 35-32 while dropping the Reds to 32-35 amid bullpen woes.

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With two outs and the score tied in the ninth, Fernando Tatis Jr. crushed a slider over the left-field wall, sending Petco Park into a frenzy as teammates mobbed him at the plate.

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The Nigeria Football Federation extended Eric Chelle's contract through 2030, adding U-23 Olympic Eagles oversight to his Super Eagles job after Nigeria's recent AFCON bronze and missed 2026 World Cup. Finidi, now with Rivers United, reportedly calls the dual role too demanding, arguing it distracts from youth development, though the claim lacks his direct confirmation and some journalists label it unverified. Fans split, with some blaming Finidi's past tenure and others citing past successes like Jo Bonfrere's 1990s double duty that led to Olympic gold.

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Finidi George, once at the helm of Nigeria's Super Eagles, is speaking out against loading extra duties onto the current coach. His concern centers on whether one person can truly handle both the senior team and the Olympic hopefuls.

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The 18-year-old Argentine, wearing No. 30 for Los Blancos, got the ink to celebrate Messi's victory over France on December 18, 2022. Mastantuono, a huge Messi fan, explained in interviews: 'I have 18/12/22 tattooed because of Messi. He is my idol.' He even picked jersey number 30 to nod to Messi's early Barcelona and PSG days. Now sharing a locker room with Kylian Mbappé, who scored a hat-trick in that final, Mastantuono's tattoo highlights Messi's lasting inspiration for the next generation.

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Real Madrid's young star Franco Mastantuono has a tattoo on his arm and neck—numbers 18, 12, and 22—that mark the exact day Lionel Messi lifted the World Cup for Argentina.

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Nebius Group ($NBIS) has climbed over 229% year-to-date to $283.61, boosted by Nvidia, Microsoft, and Meta partnerships plus Nasdaq-100 inclusion, with analysts eyeing $15 billion revenue by 2028. IREN Limited ($IREN) dropped 5.15% to $56.87 despite a $9.7 billion Microsoft deal and plans for 140,000 GPUs targeting $3.4 billion AI revenue by late 2026, though mining still dominates its income. Chatter splits between Nebius's cleaner growth and IREN's power assets as a long-term edge, with a June 23 X Spaces set to feature company reps discussing the shift.

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Two AI cloud contenders, IREN and Nebius, have investors picking sides as one surges and the other dips amid booming data center demand.

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Inter Milan have secured 32-year-old Italian goalkeeper Ivan Provedel from Lazio for €3 million to serve as backup to new No. 1 Josep Martinez next season. The move replaces Yann Sommer, who left after turning down a reserve role, with Provedel bringing strong Serie A stats like 3.13 saves per 90 minutes and reliable distribution. His agent highlighted Provedel's lifelong fandom, and fans praised the smart, budget-friendly addition for squad depth as Inter prepare to defend their title.

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Ivan Provedel, a lifelong Inter fan, is closing the circle on his dream move after agreeing to a pay cut and a three-year deal.

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Notts County, fifth in the 2025-26 League Two table with 80 points, earned a narrow away win thanks to Jayden Luker's 28th-minute goal in the first leg. The second leg at 8 p.m. sets a new attendance record of 17,000, topping their previous high of 16,264 and outpacing most lower-tier crowds this season. Manager Martin Paterson cautioned that progression to the Wembley final against Salford City or Grimsby Town isn't guaranteed, but with the Kop stand primed to roar, fans from emptier days are dreaming big.

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Meadow Lane will roar with 17,000 fans on Friday as Notts County defends their 1-0 lead over Chesterfield in the League Two play-off semi-final.

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Luciano Darderi came back from a set and a break down to beat Tommy Paul 3-6, 6-3, 6-2 at the Italian Open in Rome. The win advances Darderi to his first Masters 1000 Round of 16 in front of the home Italian crowd.

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Federico Valverde experienced a challenging season as captain of both Real Madrid and Uruguay, marked by chemistry issues, undermined coaches, a historical $500,000 fine for a training ground altercation, and leading coups against managers. Discussions highlight his past controversies including punching and receiving a red card against Baena, refusing positions, lack of effort in warm-ups, and his wife's criticism of Carlo Ancelotti.

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The 30-year-old Italian midfielder triggered his release clause from Anorthosis Famagusta and agreed a deal with CSKA Sofia until 2028. After dazzling at Sassuolo and winning two Scudetti with Inter, injuries sidelined him through loans, but he shone in Cyprus with top stats in progressive passes, tackles, and defensive actions. CSKA, last season's Bulgarian league runners-up, see his Serie A pedigree as key to chasing European spots in a club with a history of legends like Stoichkov and Berbatov.

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From Inter Milan's San Siro highs to a €200k bargain in Bulgaria, Stefano Sensi is chasing a fresh start with CSKA Sofia.

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Profluent, an Emeryville-based AI biotech startup founded in 2022 by Ali Madani, raised $106 million on November 19, 2025, led by Altimeter Capital and Bezos Expeditions, bringing its total funding to $150 million and valuing it at nearly $1 billion. The company has achieved breakthroughs like the AI-designed OpenCRISPR-1 system for precise genome editing and ProGen models generating functional proteins. The new funds will scale computational resources for massive protein datasets and advance applications in therapeutics, agriculture, and materials.

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Jeff Bezos's investment fuels Profluent's quest to design proteins and genome editors using AI, pushing biotech boundaries.

Kontext & Entitaten

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Coldplay Access shared a dramatic announcement Tuesday claiming the band was splitting after Moon Music and their tour, with Chris Martin eyeing Hollywood and Jonny Buckland tending sheep. Heartbroken reactions flooded in, like one user's 'BITCH MY HEART SKIPPED A BEAT,' though savvy fans spotted the April Fool's joke right away. No official word from Coldplay, whose Music of the Spheres tour runs through 2026 and latest album earned strong reviews.

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A Brazilian fan account's post screamed 'THE END OF COLDPLAY!' with a 1998-2026 stamp, leaving fans pleading 'What do you mean end of Coldplay???' before realizing it was April 1.

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Jorge Mendes has offered PSG's breakout star João Neves to Real Madrid, where president Florentino Pérez rates him highly alongside Inter's commanding center-back Alessandro Bastoni. Neves, who helped PSG win the Champions League after his €60 million move from Benfica, recently extended his contract to 2029 or 2030, with PSG valuing him over €100 million. Madrid are also pursuing low-cost buy-backs on former academy players like Nico Paz, Jacobo Ramón, and Víctor Muñoz for around €23 million total, blending ambition with smart business ahead of the summer window.

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João Neves, the 21-year-old Portuguese midfielder thriving at PSG, now has his super-agent pitching a dream move to Real Madrid's Bernabéu.

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Columbus Crew's Patrick Schulte replaces FC Cincinnati's Roman Celentano, who withdrew due to muscle tightness, for the U.S. Men's National Team's friendlies against No. 7 Belgium on March 28 and Portugal on March 31. The 25-year-old Schulte, a homegrown talent with five starts and a clean sheet this season, joins Matt Freese, Matt Turner, and Chris Brady in a crowded goalkeeper group where spots three and four remain contested. These matches in Atlanta mark Pochettino's final tune-ups before finalizing his World Cup roster this summer, giving Schulte a key audition ahead of the home tournament.

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Patrick Schulte stepped into USMNT camp Sunday, ready to battle for a keeper spot as coach Pochettino fine-tunes his squad for the 2026 World Cup.

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Filippo Sorcinelli, 50, owns Atelier LAVS in Rimini and has crafted sacred vestments for Popes Benedict XVI, Francis, and Leo XIV over two decades. Openly gay and a practicing Catholic, he views faith and sexuality as creative tension, not conflict. The photo has drawn praise for highlighting queer influence in Catholic art, from Michelangelo's frescoes to modern designs, though some conservatives question his role. Many see it as proof that talent and devotion cross all divides.

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Picture this: a bald, earring-wearing Italian designer in a sharp black suit kneels to fix the golden robes on a Virgin Mary statue, surrounded by Vatican art. It's a moment of devotion that's captured hearts online.

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